BDBM8960 (+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-indan-1-one::2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one::Aricept::Aricept odt::CHEMBL1678::CHEMBL2337271::CHEMBL502::DONEPEZIL HYDROCHLORIDE::Donepezil::Donepzil::E2020::US8999994, Donepezil::US9346818, DPH::US9586925, Donepezil::US9663465, Donepezil
SMILES COc1cc2CC(CC3CCN(Cc4ccccc4)CC3)C(=O)c2cc1OC
InChI Key InChIKey=ADEBPBSSDYVVLD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 8960
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
Affinity DataIC50: 169nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of human BACE1 using as 7-Methoxycoumarin-4-acetyl-[Asn670, Leu671]-Amyloid beta/A4 precursor protein 770 fragment 667-676-(2,4-dinitrophe...More data for this Ligand-Target Pair
Affinity DataIC50: 362nMAssay Description:Inhibition of human BACE-1 using MOCA-SEV-NL-DAEFR-DNP-RR as substrate preincubated with substrate followed by enzyme addition by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 362nMAssay Description:Inhibition of human BACE-1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant BACE1More data for this Ligand-Target Pair